Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition

BACKGROUND: Histone deacetylase inhibitors (HDACis) like vorinostat are promising radiosensitisers in prostate cancer, but their effect under hypoxia is not known. We investigated gene expression associated with radiosensitisation of normoxic and hypoxic prostate cancer cells by vorinostat. METHODS:...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Jonsson, Marte, Ragnum, Harald Bull, Julin, Cathinka Halle, Yeramian, Andree, Clancy, Trevor, Frikstad, Kari-Anne Myrum, Seierstad, Therese, Stokke, Trond, Matias-Guiu, Xavier, Ree, Anne Hansen, Flatmark, Kjersti, Lyng, Heidi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061908/
https://ncbi.nlm.nih.gov/pubmed/27599042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.278
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