Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition

BACKGROUND: Histone deacetylase inhibitors (HDACis) like vorinostat are promising radiosensitisers in prostate cancer, but their effect under hypoxia is not known. We investigated gene expression associated with radiosensitisation of normoxic and hypoxic prostate cancer cells by vorinostat. METHODS:...

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Publicat a:Br J Cancer
Autors principals: Jonsson, Marte, Ragnum, Harald Bull, Julin, Cathinka Halle, Yeramian, Andree, Clancy, Trevor, Frikstad, Kari-Anne Myrum, Seierstad, Therese, Stokke, Trond, Matias-Guiu, Xavier, Ree, Anne Hansen, Flatmark, Kjersti, Lyng, Heidi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Translational Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061908/
https://ncbi.nlm.nih.gov/pubmed/27599042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.278
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