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Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition

BACKGROUND: Histone deacetylase inhibitors (HDACis) like vorinostat are promising radiosensitisers in prostate cancer, but their effect under hypoxia is not known. We investigated gene expression associated with radiosensitisation of normoxic and hypoxic prostate cancer cells by vorinostat. METHODS:...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Br J Cancer
Main Authors: Jonsson, Marte, Ragnum, Harald Bull, Julin, Cathinka Halle, Yeramian, Andree, Clancy, Trevor, Frikstad, Kari-Anne Myrum, Seierstad, Therese, Stokke, Trond, Matias-Guiu, Xavier, Ree, Anne Hansen, Flatmark, Kjersti, Lyng, Heidi
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061908/
https://ncbi.nlm.nih.gov/pubmed/27599042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.278
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