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Comparison between the comet assay and pimonidazole binding for measuring tumour hypoxia

Pimonidazole is finding increasing use in histochemical analyses of hypoxia in tumours. Whether it can identify every hypoxic cell in a tumour, and whether the usual subjective criteria used to define ‘positive’ cells are optimal, are less certain. Therefore, our aim was to develop an objective flow...

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Autori principali: Olive, P L, Durand, R E, Raleigh, J A, Luo, C, Aquino-Parsons, C
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363410/
https://ncbi.nlm.nih.gov/pubmed/11076663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1489
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