Subducted and Melanotic Cells in Advanced Age-Related Macular Degeneration Are Derived From Retinal Pigment Epithelium

PURPOSE. To describe, illustrate, and account for two cell types plausibly derived from RPE in geographic atrophy (GA) and choroidal neovascularization (CNV) of AMD, using melanosomes, lipofuscin, and basal laminar deposit (BLamD) as anatomical markers. METHODS. Human donor eyes with GA (n = 13) or...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Invest Ophthalmol Vis Sci
Main Authors: Zanzottera, Emma C., Messinger, Jeffrey D., Ach, Thomas, Smith, R. Theodore, Curcio, Christine A.
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2015
Teme:
Retina
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453434/
https://ncbi.nlm.nih.gov/pubmed/26024109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-16432
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