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Quantifying Retinal Pigment Epithelium Dysmorphia and Loss of Histologic Autofluorescence in Age-Related Macular Degeneration

PURPOSE: Lipofuscin and melanolipofuscin organelles in retinal pigment epithelium (RPE) cells are signal sources for clinical fundus autofluorescence (AF). To elucidate the subcellular basis of AF imaging, we identified, characterized, and quantified the frequency of RPE morphology and AF phenotypes...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Gambril, J. Alan, Sloan, Kenneth R., Swain, Thomas A., Huisingh, Carrie, Zarubina, Anna V., Messinger, Jeffrey D., Ach, Thomas, Curcio, Christine A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557619/
https://ncbi.nlm.nih.gov/pubmed/31173079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.19-26949
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