Quantifying Retinal Pigment Epithelium Dysmorphia and Loss of Histologic Autofluorescence in Age-Related Macular Degeneration

PURPOSE: Lipofuscin and melanolipofuscin organelles in retinal pigment epithelium (RPE) cells are signal sources for clinical fundus autofluorescence (AF). To elucidate the subcellular basis of AF imaging, we identified, characterized, and quantified the frequency of RPE morphology and AF phenotypes...

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Pubblicato in:Invest Ophthalmol Vis Sci
Autori principali: Gambril, J. Alan, Sloan, Kenneth R., Swain, Thomas A., Huisingh, Carrie, Zarubina, Anna V., Messinger, Jeffrey D., Ach, Thomas, Curcio, Christine A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Association for Research in Vision and Ophthalmology 2019
Soggetti:
Retina
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557619/
https://ncbi.nlm.nih.gov/pubmed/31173079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.19-26949
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