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Conformational Changes in the Orai1 C-Terminus Evoked by STIM1 Binding
Store-operated CRAC channels regulate a wide range of cellular functions including gene expression, chemotaxis, and proliferation. CRAC channels consist of two components: the Orai proteins (Orai1-3), which form the ion-selective pore, and STIM proteins (STIM1-2), which form the endoplasmic reticulu...
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| Udgivet i: | PLoS One |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4452722/ https://ncbi.nlm.nih.gov/pubmed/26035642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128622 |
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