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STIM1–Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy
Ca(2+) entry through store-operated Ca(2+) release-activated Ca(2+) (CRAC) channels initiates key functions such as gene expression and exocytosis of inflammatory mediators. Activation of CRAC channels by store depletion involves the redistribution of the ER Ca(2+) sensor, stromal interaction molecu...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Blackwell Science Inc
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2655373/ https://ncbi.nlm.nih.gov/pubmed/18832420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.162503 |
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