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STIM1–Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy

Ca(2+) entry through store-operated Ca(2+) release-activated Ca(2+) (CRAC) channels initiates key functions such as gene expression and exocytosis of inflammatory mediators. Activation of CRAC channels by store depletion involves the redistribution of the ER Ca(2+) sensor, stromal interaction molecu...

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Detalhes bibliográficos
Main Authors: Navarro-Borelly, Laura, Somasundaram, Agila, Yamashita, Megumi, Ren, Dongjun, Miller, Richard J, Prakriya, Murali
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655373/
https://ncbi.nlm.nih.gov/pubmed/18832420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.162503
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