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Microglia Disrupt Mesolimbic Reward Circuitry in Chronic Pain
Chronic pain attenuates midbrain dopamine (DA) transmission, as evidenced by a decrease in opioid-evoked DA release in the ventral striatum, suggesting that the occurrence of chronic pain impairs reward-related behaviors. However, mechanisms by which pain modifies DA transmission remain elusive. Usi...
Shranjeno v:
| izdano v: | J Neurosci |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Society for Neuroscience
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4452552/ https://ncbi.nlm.nih.gov/pubmed/26041913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4036-14.2015 |
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