Neuroimmune Regulation of GABAergic Neurons Within the Ventral Tegmental Area During Withdrawal from Chronic Morphine

Opioid dependence is accompanied by neuroplastic changes in reward circuitry leading to a negative affective state contributing to addictive behaviors and risk of relapse. The current study presents a neuroimmune mechanism through which chronic opioids disrupt the ventral tegmental area (VTA) dopami...

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Veröffentlicht in:Neuropsychopharmacology
Hauptverfasser: Taylor, Anna M W, Castonguay, Annie, Ghogha, Atefeh, Vayssiere, Pia, Pradhan, Amynah A A, Xue, Lihua, Mehrabani, Sadaf, Wu, Juli, Levitt, Pat, Olmstead, Mary C, De Koninck, Yves, Evans, Christopher J, Cahill, Catherine M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748420/
https://ncbi.nlm.nih.gov/pubmed/26202104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.221
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