Differential Inhibition of Human Atherosclerotic Plaque–Induced Platelet Activation by Dimeric GPVI-Fc and Anti-GPVI Antibodies: Functional and Imaging Studies

BACKGROUND: Glycoprotein VI (GPVI) is the essential platelet collagen receptor in atherothrombosis, but its inhibition causes only a mild bleeding tendency. Thus, targeting this receptor has selective antithrombotic potential. OBJECTIVES: This study sought to compare compounds interfering with plate...

詳細記述

保存先:
書誌詳細
出版年:J Am Coll Cardiol
主要な著者: Jamasbi, Janina, Megens, Remco T.A., Bianchini, Mariaelvy, Münch, Götz, Ungerer, Martin, Faussner, Alexander, Sherman, Shachar, Walker, Adam, Goyal, Pankaj, Jung, Stephanie, Brandl, Richard, Weber, Christian, Lorenz, Reinhard, Farndale, Richard, Elia, Natalie, Siess, Wolfgang
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier Biomedical 2015
主題:
Original Investigation
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452546/
https://ncbi.nlm.nih.gov/pubmed/26046734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2015.03.573
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