The GPVI-Fc Fusion Protein Revacept Improves Cerebral Infarct Volume and Functional Outcome in Stroke

OBJECTIVES: We examined the effect of Revacept, an Fc fusion protein which is specifically linked to the extracellular domain of glycoprotein VI (GPVI), on thrombus formation after vessel wall injury and on experimental stroke in mice. BACKGROUND: Several antiplatelet drugs for the treatment of myoc...

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Main Authors: Goebel, Silvia, Li, Zhongmin, Vogelmann, Jasmin, Holthoff, Hans-Peter, Degen, Heidrun, Hermann, Dirk M., Gawaz, Meinrad, Ungerer, Martin, Münch, Götz
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720811/
https://ncbi.nlm.nih.gov/pubmed/23935828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066960
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