The GPVI-Fc Fusion Protein Revacept Improves Cerebral Infarct Volume and Functional Outcome in Stroke

OBJECTIVES: We examined the effect of Revacept, an Fc fusion protein which is specifically linked to the extracellular domain of glycoprotein VI (GPVI), on thrombus formation after vessel wall injury and on experimental stroke in mice. BACKGROUND: Several antiplatelet drugs for the treatment of myoc...

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Main Authors: Goebel, Silvia, Li, Zhongmin, Vogelmann, Jasmin, Holthoff, Hans-Peter, Degen, Heidrun, Hermann, Dirk M., Gawaz, Meinrad, Ungerer, Martin, Münch, Götz
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720811/
https://ncbi.nlm.nih.gov/pubmed/23935828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066960
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