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The GPVI – Fc Fusion Protein Revacept Reduces Thrombus Formation and Improves Vascular Dysfunction in Atherosclerosis without Any Impact on Bleeding Times

AIMS: Glycoprotein VI (GPVI) is a key platelet receptor which mediates plaque-induced platelet activation and consecutive atherothrombosis, but GPVI is also involved in platelet-mediated atheroprogression. Therefore, interference in GPVI-mediated platelet activation has the potential to combine shor...

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Autors principals: Ungerer, Martin, Li, Zhongmin, Baumgartner, Christine, Goebel, Silvia, Vogelmann, Jasmin, Holthoff, Hans-Peter, Gawaz, Meinrad, Münch, Götz
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741334/
https://ncbi.nlm.nih.gov/pubmed/23951109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071193
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