Amino Acid Substitutions Improve the Immunogenicity of H7N7HA Protein and Protect Mice against Lethal H7N7 Viral Challenge

Avian influenza A H7N7/NL/219/03 virus creates a serious pandemic threat to human health because it can transmit directly from domestic poultry to humans and from human to human. Our previous vaccine study reported that mice when immunized intranasally (i.n) with live Bac-HA were protected from leth...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: kumar, Subaschandrabose Rajesh, Prabakaran, Mookkan, Ashok raj, Kattur Venkatachalam, He, Fang, Kwang, Jimmy
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452345/
https://ncbi.nlm.nih.gov/pubmed/26030920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128940
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