Intranasal Immunization of Baculovirus Displayed Hemagglutinin Confers Complete Protection against Mouse Adapted Highly Pathogenic H7N7 Reassortant Influenza Virus

BACKGROUND: Avian influenza A H7N7 virus poses a pandemic threat to human health because of its ability for direct transmission from domestic poultry to humans and from human to human. The wide zoonotic potential of H7N7 combined with an antiviral immunity inhibition similar to pandemic 1918 H1N1 an...

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Detalhes bibliográficos
Main Authors: Rajesh Kumar, Subaschandrabose, Syed Khader, Syed Musthaq, Kiener, Tanja K., Szyporta, Milene, Kwang, Jimmy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676417/
https://ncbi.nlm.nih.gov/pubmed/23762234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063856
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