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Monoclonal Antibodies against the Fusion Peptide of Hemagglutinin Protect Mice from Lethal Influenza A Virus H5N1 Infection

The HA2 glycopolypeptide (gp) is highly conserved in all influenza A virus strains, and it is known to play a major role in the fusion of the virus with the endosomal membrane in host cells during the course of viral infection. Vaccines and therapeutics targeting this HA2 gp could induce efficient b...

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Detalhes bibliográficos
Main Authors: Prabhu, Nayana, Prabakaran, Mookkan, Ho, Hui-Ting, Velumani, Sumathy, Qiang, Jia, Goutama, Michael, Kwang, Jimmy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648274/
https://ncbi.nlm.nih.gov/pubmed/19109379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02165-08
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