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Monoclonal Antibodies against the Fusion Peptide of Hemagglutinin Protect Mice from Lethal Influenza A Virus H5N1 Infection

The HA2 glycopolypeptide (gp) is highly conserved in all influenza A virus strains, and it is known to play a major role in the fusion of the virus with the endosomal membrane in host cells during the course of viral infection. Vaccines and therapeutics targeting this HA2 gp could induce efficient b...

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Dettagli Bibliografici
Autori principali: Prabhu, Nayana, Prabakaran, Mookkan, Ho, Hui-Ting, Velumani, Sumathy, Qiang, Jia, Goutama, Michael, Kwang, Jimmy
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648274/
https://ncbi.nlm.nih.gov/pubmed/19109379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02165-08
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