Amino Acid Substitutions Improve the Immunogenicity of H7N7HA Protein and Protect Mice against Lethal H7N7 Viral Challenge

Avian influenza A H7N7/NL/219/03 virus creates a serious pandemic threat to human health because it can transmit directly from domestic poultry to humans and from human to human. Our previous vaccine study reported that mice when immunized intranasally (i.n) with live Bac-HA were protected from leth...

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Опубликовано в: :PLoS One
Главные авторы: kumar, Subaschandrabose Rajesh, Prabakaran, Mookkan, Ashok raj, Kattur Venkatachalam, He, Fang, Kwang, Jimmy
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452345/
https://ncbi.nlm.nih.gov/pubmed/26030920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128940
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