Suppression of silent information regulator 1 activity in noncancerous tissues of hepatocellular carcinoma: Possible association with non-B non-C hepatitis pathogenesis

Silent information regulator 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD(+))-dependent protein deacetylase. In mice, mSirt1 deficiency causes the onset of fatty liver via regulation of the hepatic nutrient metabolism pathway. In this study, we demonstrate SIRT1 expression, activity and NAD...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Sci
Egile Nagusiak: Konishi, Hideyuki, Shirabe, Ken, Nakagawara, Hidekazu, Harimoto, Norifumi, Yamashita, Yo-Ichi, Ikegami, Toru, Yoshizumi, Tomoharu, Soejima, Yuji, Oda, Yoshinao, Maehara, Yoshihiko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BlackWell Publishing Ltd 2015
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452154/
https://ncbi.nlm.nih.gov/pubmed/25736100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12653
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