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Regulation of system x(c)(−) activity and expression in astrocytes by interleukin-1β: implications for hypoxic neuronal injury
We recently demonstrated that interleukin-1β (IL-1β) increases system x(c)(−) (cystine/glutamate antiporter) activity in mixed cortical cell cultures, resulting in an increase in hypoxic neuronal injury when glutamate clearance is impaired. Herein, we demonstrate that neurons, astrocytes and microgl...
Gorde:
| Argitaratua izan da: | Glia |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2010
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4451603/ https://ncbi.nlm.nih.gov/pubmed/20645408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21050 |
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