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Non-cell autonomous influence of the astrocyte system x(c)(−) on hypoglycaemic neuronal cell death

Despite longstanding evidence that hypoglycaemic neuronal injury is mediated by glutamate excitotoxicity, the cellular and molecular mechanisms involved remain incompletely defined. Here, we demonstrate that the excitotoxic neuronal death that follows GD (glucose deprivation) is initiated by glutama...

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Detalhes bibliográficos
Main Authors: Jackman, Nicole A, Melchior, Shannon E, Hewett, James A, Hewett, Sandra J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Neurochemistry 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275339/
https://ncbi.nlm.nih.gov/pubmed/22220511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20110030
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