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System x(c)(−) Activity and Astrocytes Are Necessary for Interleukin-1β-Mediated Hypoxic Neuronal Injury

The purpose of this study was to elucidate the cellular/biochemical pathway(s) by which interleukin-1β (IL-1β) contributes to the pathogenesis of hypoxic–ischemic brain damage. In vivo, IL-1 receptor type I (IL-1RI)-deficient mice showed smaller infarcts and less neurological deficits than wild-type...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Fogal, Birgit, Li, Jun, Lobner, Doug, McCullough, Louise D., Hewett, Sandra J.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672668/
https://ncbi.nlm.nih.gov/pubmed/17881516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2459-07.2007
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