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System x(c)(−) Activity and Astrocytes Are Necessary for Interleukin-1β-Mediated Hypoxic Neuronal Injury
The purpose of this study was to elucidate the cellular/biochemical pathway(s) by which interleukin-1β (IL-1β) contributes to the pathogenesis of hypoxic–ischemic brain damage. In vivo, IL-1 receptor type I (IL-1RI)-deficient mice showed smaller infarcts and less neurological deficits than wild-type...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6672668/ https://ncbi.nlm.nih.gov/pubmed/17881516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2459-07.2007 |
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