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Free Energy Landscape and Multiple Folding Pathways of an H-Type RNA Pseudoknot
How RNA sequences fold to specific tertiary structures is one of the key problems for understanding their dynamics and functions. Here, we study the folding process of an H-type RNA pseudoknot by performing a large-scale all-atom MD simulation and bias-exchange metadynamics. The folding free energy...
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| Yayımlandı: | PLoS One |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4451515/ https://ncbi.nlm.nih.gov/pubmed/26030098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129089 |
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