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Free Energy Landscape and Multiple Folding Pathways of an H-Type RNA Pseudoknot

How RNA sequences fold to specific tertiary structures is one of the key problems for understanding their dynamics and functions. Here, we study the folding process of an H-type RNA pseudoknot by performing a large-scale all-atom MD simulation and bias-exchange metadynamics. The folding free energy...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Bian, Yunqiang, Zhang, Jian, Wang, Jun, Wang, Jihua, Wang, Wei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451515/
https://ncbi.nlm.nih.gov/pubmed/26030098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129089
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