Učitavanje...

Rational design of allosteric-inhibition sites in classical protein tyrosine phosphatases

Protein tyrosine phosphatases (PTPs), which catalyze the dephosphorylation of phosphotyrosine in protein substrates, are critical regulators of metazoan cell signaling and have emerged as potential drug targets for a range of human diseases. Strategies for chemically targeting the function of indivi...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Bioorg Med Chem
Glavni autori: Chio, Cynthia M., Yu, Xiaoling, Bishop, Anthony C.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451255/
https://ncbi.nlm.nih.gov/pubmed/25828055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.03.027
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!