Llwytho...

Rational design of allosteric-inhibition sites in classical protein tyrosine phosphatases

Protein tyrosine phosphatases (PTPs), which catalyze the dephosphorylation of phosphotyrosine in protein substrates, are critical regulators of metazoan cell signaling and have emerged as potential drug targets for a range of human diseases. Strategies for chemically targeting the function of indivi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioorg Med Chem
Prif Awduron: Chio, Cynthia M., Yu, Xiaoling, Bishop, Anthony C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451255/
https://ncbi.nlm.nih.gov/pubmed/25828055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.03.027
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