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Role of Genetic Polymorphisms of Deoxycytidine Kinase and Cytidine Deaminase to Predict Risk of Death in Children with Acute Myeloid Leukemia

Cytarabine is one of the most effective antineoplastic agents among those used for the treatment of acute myeloid leukemia. However, some patients develop resistance and/or severe side effects to the drug, which may interfere with the efficacy of the treatment. The polymorphisms of some Ara-C metabo...

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Dettagli Bibliografici
Pubblicato in:Biomed Res Int
Autori principali: Medina-Sanson, Aurora, Ramírez-Pacheco, Arturo, Moreno-Guerrero, Silvia Selene, Dorantes-Acosta, Elisa María, Sánchez-Preza, Metzeri, Reyes-López, Alfonso
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450239/
https://ncbi.nlm.nih.gov/pubmed/26090398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/309491
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