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Role of Genetic Polymorphisms of Deoxycytidine Kinase and Cytidine Deaminase to Predict Risk of Death in Children with Acute Myeloid Leukemia

Cytarabine is one of the most effective antineoplastic agents among those used for the treatment of acute myeloid leukemia. However, some patients develop resistance and/or severe side effects to the drug, which may interfere with the efficacy of the treatment. The polymorphisms of some Ara-C metabo...

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Bibliografiske detaljer
Udgivet i:Biomed Res Int
Main Authors: Medina-Sanson, Aurora, Ramírez-Pacheco, Arturo, Moreno-Guerrero, Silvia Selene, Dorantes-Acosta, Elisa María, Sánchez-Preza, Metzeri, Reyes-López, Alfonso
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450239/
https://ncbi.nlm.nih.gov/pubmed/26090398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/309491
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