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Paclitaxel alters the expression and specific activity of deoxycytidine kinase and cytidine deaminase in non-small cell lung cancer cell lines

BACKGROUND: We observed that paclitaxel altered the pharmacokinetic properties of gemcitabine in patients with non-small cell lung cancer (NSCLC) and limited the accumulation of gemcitabine and its metabolites in various primary and immortalized human cells. Therefore, we classified the drug-drug in...

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Hlavní autoři: Shord, Stacy S, Patel, Shitalben R
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708129/
https://ncbi.nlm.nih.gov/pubmed/19500405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-28-76
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