Molecular and functional significance of Ca(2+)-activated Cl(−) channels in pulmonary arterial smooth muscle

Abstract. Increased peripheral resistance of small distal pulmonary arteries is a hallmark signature of pulmonary hypertension (PH) and is believed to be the consequence of enhanced vasoconstriction to agonists, thickening of the arterial wall due to remodeling, and increased thrombosis. The elevati...

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Dades bibliogràfiques
Publicat a:Pulm Circ
Autors principals: Leblanc, Normand, Forrest, Abigail S., Ayon, Ramon J., Wiwchar, Michael, Angermann, Jeff E., Pritchard, Harry A. T., Singer, Cherie A., Valencik, Maria L., Britton, Fiona, Greenwood, Iain A.
Format: Artigo
Idioma:Inglês
Publicat: University of Chicago Press 2015
Matèries:
Review Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449236/
https://ncbi.nlm.nih.gov/pubmed/26064450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/680189
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