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Phosphorylation alters the pharmacology of Ca(2+)-activated Cl(−) channels in rabbit pulmonary arterial smooth muscle cells
BACKGROUND AND PURPOSE: Ca(2+)-activated Cl(−) currents (I(Cl(Ca))) in arterial smooth muscle cells are inhibited by phosphorylation. The Ca(2+)-activated Cl(−) channel (Cl(Ca)) blocker niflumic acid (NFA) produces a paradoxical dual effect on I(Cl(Ca)), causing stimulation or inhibition at potentia...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Publishing Ltd
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782345/ https://ncbi.nlm.nih.gov/pubmed/19785656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00405.x |
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