Molecular and functional significance of Ca(2+)-activated Cl(−) channels in pulmonary arterial smooth muscle

Abstract. Increased peripheral resistance of small distal pulmonary arteries is a hallmark signature of pulmonary hypertension (PH) and is believed to be the consequence of enhanced vasoconstriction to agonists, thickening of the arterial wall due to remodeling, and increased thrombosis. The elevati...

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Bibliographic Details
Published in:Pulm Circ
Main Authors: Leblanc, Normand, Forrest, Abigail S., Ayon, Ramon J., Wiwchar, Michael, Angermann, Jeff E., Pritchard, Harry A. T., Singer, Cherie A., Valencik, Maria L., Britton, Fiona, Greenwood, Iain A.
Format: Artigo
Language:Inglês
Published: University of Chicago Press 2015
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Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449236/
https://ncbi.nlm.nih.gov/pubmed/26064450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/680189
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