Molecular and functional significance of Ca(2+)-activated Cl(−) channels in pulmonary arterial smooth muscle

Abstract. Increased peripheral resistance of small distal pulmonary arteries is a hallmark signature of pulmonary hypertension (PH) and is believed to be the consequence of enhanced vasoconstriction to agonists, thickening of the arterial wall due to remodeling, and increased thrombosis. The elevati...

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Detalles Bibliográficos
Publicado en:Pulm Circ
Main Authors: Leblanc, Normand, Forrest, Abigail S., Ayon, Ramon J., Wiwchar, Michael, Angermann, Jeff E., Pritchard, Harry A. T., Singer, Cherie A., Valencik, Maria L., Britton, Fiona, Greenwood, Iain A.
Formato: Artigo
Idioma:Inglês
Publicado: University of Chicago Press 2015
Assuntos:
Review Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449236/
https://ncbi.nlm.nih.gov/pubmed/26064450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/680189
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