Molecular mechanism of TMEM16A regulation: role of CaMKII and PP1/PP2A

This study explored the mechanism by which Ca(2+)-activated Cl(−) channels (CaCCs) encoded by the Tmem16a gene are regulated by calmodulin-dependent protein kinase II (CaMKII) and protein phosphatases 1 (PP1) and 2A (PP2A). Ca(2+)-activated Cl(−) currents (I(ClCa)) were recorded from HEK-293 cells e...

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Publicat a:Am J Physiol Cell Physiol
Autors principals: Ayon, Ramon J., Hawn, Matthew B., Aoun, Joydeep, Wiwchar, Michael, Forrest, Abigail S., Cunningham, Fiona, Singer, Cherie A., Valencik, Maria L., Greenwood, Iain A., Leblanc, Normand
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2019
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957382/
https://ncbi.nlm.nih.gov/pubmed/31461344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00059.2018
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