Increased TMEM16A-encoded calcium-activated chloride channel activity is associated with pulmonary hypertension

Pulmonary artery smooth muscle cells (PASMCs) are more depolarized and display higher Ca(2+) levels in pulmonary hypertension (PH). Whether the functional properties and expression of Ca(2+)-activated Cl− channels (Cl(Ca)), an important excitatory mechanism in PASMCs, are altered in PH is unknown. T...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Forrest, Abigail S., Joyce, Talia C., Huebner, Marissa L., Ayon, Ramon J., Wiwchar, Michael, Joyce, John, Freitas, Natalie, Davis, Alison J., Ye, Linda, Duan, Dayue D., Singer, Cherie A., Valencik, Maria L., Greenwood, Iain A., Leblanc, Normand
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2012
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532492/
https://ncbi.nlm.nih.gov/pubmed/23034390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00044.2012
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki