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Specificity of the Anaphase Promoting Complex: a single-molecule study

Biological processes require specific enzymatic reactions, paradoxically involving short recognition sequences. As an example, cell-cycle timing depends on a sequence of ubiquitylation events mediated by the Anaphase Promoting Complex (APC) based on short redundant motifs. To understand the origin o...

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Bibliographic Details
Published in:Science
Main Authors: Lu, Ying, Wang, Weiping, Kirschner, Marc W.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449139/
https://ncbi.nlm.nih.gov/pubmed/25859049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1248737
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