Acyclovir Has Low but Detectable Influence on HLA-B*57:01 Specificity without Inducing Hypersensitivity

Immune mediated adverse drug reactions (IM-ADRs) remain a significant source of patient morbidity that have more recently been shown to be associated with specific class I and/or II human leukocyte antigen (HLA) alleles. Abacavir-induced hypersensitivity syndrome is a CD8(+) T cell dependent IM-ADR...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Metushi, Imir G., Wriston, Amanda, Banerjee, Priyanka, Gohlke, Bjoern Oliver, English, A. Michelle, Lucas, Andrew, Moore, Carrie, Sidney, John, Buus, Soren, Ostrov, David A., Mallal, Simon, Phillips, Elizabeth, Shabanowitz, Jeffrey, Hunt, Donald F., Preissner, Robert, Peters, Bjoern
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449000/
https://ncbi.nlm.nih.gov/pubmed/26024233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124878
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