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HLA-B*57:01 allele prevalence in HIV-infected North American subjects and the impact of allele testing on the incidence of abacavir-associated hypersensitivity reaction in HLA-B*57:01-negative subjects

BACKGROUND: The presence of the HLA-B*57:01 allele in HIV-infected subjects is associated with a higher risk of abacavir-associated hypersensitivity reaction (ABC HSR). HLA-B*57:01 allele prevalence varies in different populations, but HLA-B*57:01 testing with immunological confirmation has had a ne...

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Detalhes bibliográficos
Publicado no:BMC Infect Dis
Main Authors: Small, Catherine Butkus, Margolis, David A., Shaefer, Mark S., Ross, Lisa L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387336/
https://ncbi.nlm.nih.gov/pubmed/28399804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-017-2331-y
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