mTOR Is Essential for Growth and Proliferation in Early Mouse Embryos and Embryonic Stem Cells

TOR is a serine-threonine kinase that was originally identified as a target of rapamycin in Saccharomyces cerevisiae and then found to be highly conserved among eukaryotes. In Drosophila melanogaster, inactivation of TOR or its substrate, S6 kinase, results in reduced cell size and embryonic lethali...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Murakami, Mirei, Ichisaka, Tomoko, Maeda, Mitsuyo, Oshiro, Noriko, Hara, Kenta, Edenhofer, Frank, Kiyama, Hiroshi, Yonezawa, Kazuyoshi, Yamanaka, Shinya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2004
Schlagworte:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC444840/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15254238/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.15.6710-6718.2004
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge