mTOR Is Essential for Growth and Proliferation in Early Mouse Embryos and Embryonic Stem Cells

TOR is a serine-threonine kinase that was originally identified as a target of rapamycin in Saccharomyces cerevisiae and then found to be highly conserved among eukaryotes. In Drosophila melanogaster, inactivation of TOR or its substrate, S6 kinase, results in reduced cell size and embryonic lethali...

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Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Murakami, Mirei, Ichisaka, Tomoko, Maeda, Mitsuyo, Oshiro, Noriko, Hara, Kenta, Edenhofer, Frank, Kiyama, Hiroshi, Yonezawa, Kazuyoshi, Yamanaka, Shinya
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2004
Aiheet:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC444840/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15254238/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.15.6710-6718.2004
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