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mTOR Is Essential for Growth and Proliferation in Early Mouse Embryos and Embryonic Stem Cells
TOR is a serine-threonine kinase that was originally identified as a target of rapamycin in Saccharomyces cerevisiae and then found to be highly conserved among eukaryotes. In Drosophila melanogaster, inactivation of TOR or its substrate, S6 kinase, results in reduced cell size and embryonic lethali...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2004
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC444840/ https://ncbi.nlm.nih.gov/pubmed/15254238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.15.6710-6718.2004 |
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