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Three-dimensional Structure of a Kunitz-type Inhibitor in Complex with an Elastase-like Enzyme
Elastase-like enzymes are involved in important diseases such as acute pancreatitis, chronic inflammatory lung diseases, and cancer. Structural insights into their interaction with specific inhibitors will contribute to the development of novel anti-elastase compounds that resist rapid oxidation and...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4447985/ https://ncbi.nlm.nih.gov/pubmed/25878249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.647586 |
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