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Three-dimensional Structure of a Kunitz-type Inhibitor in Complex with an Elastase-like Enzyme

Elastase-like enzymes are involved in important diseases such as acute pancreatitis, chronic inflammatory lung diseases, and cancer. Structural insights into their interaction with specific inhibitors will contribute to the development of novel anti-elastase compounds that resist rapid oxidation and...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: García-Fernández, Rossana, Perbandt, Markus, Rehders, Dirk, Ziegelmüller, Patrick, Piganeau, Nicolas, Hahn, Ulrich, Betzel, Christian, Chávez, María de los Ángeles, Redecke, Lars
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447985/
https://ncbi.nlm.nih.gov/pubmed/25878249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.647586
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