Peptidylprolyl Isomerase Pin1 Directly Enhances the DNA Binding Functions of Estrogen Receptor α

The transcriptional activity of estrogen receptor α (ERα), the key driver of breast cancer proliferation, is enhanced by multiple cellular interactions, including phosphorylation-dependent interaction with Pin1, a proline isomerase, which mediates cis-trans isomerization of the N-terminal Ser(P)(118...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Rajbhandari, Prashant, Ozers, Mary Szatkowski, Solodin, Natalia M., Warren, Christopher L., Alarid, Elaine T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447953/
https://ncbi.nlm.nih.gov/pubmed/25866209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.621698
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