Regulation of Estrogen Receptor α N-Terminus Conformation and Function by Peptidyl Prolyl Isomerase Pin1

Estrogen receptor alpha (ERα), a key driver of growth in the majority of breast cancers, contains an unstructured transactivation domain (AF1) in its N terminus that is a convergence point for growth factor and hormonal activation. This domain is controlled by phosphorylation, but how phosphorylatio...

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Bibliografski detalji
Glavni autori: Rajbhandari, Prashant, Finn, Greg, Solodin, Natalia M., Singarapu, Kiran K., Sahu, Sarata C., Markley, John L., Kadunc, Kelley J., Ellison-Zelski, Stephanie J., Kariagina, Anastasia, Haslam, Sandra Z., Lu, Kun Ping, Alarid, Elaine T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255769/
https://ncbi.nlm.nih.gov/pubmed/22064478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06073-11
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