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Cyclic Peptidyl Inhibitors against Human Peptidyl-Prolyl Isomerase Pin1

Peptidyl-prolyl isomerase Pin1 regulates the function and/or stability of phosphoproteins by altering the conformation of specific pSer/pThr-Pro peptide bonds. In this work, a cyclic peptide library was synthesized and screened against the catalytic domain of human Pin1. The selected inhibitors cont...

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Библиографические подробности
Главные авторы: Liu, Tao, Liu, Yu, Kao, Hung-Ying, Pei, Dehua
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841714/
https://ncbi.nlm.nih.gov/pubmed/20180533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901778v
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