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Cyclic Peptidyl Inhibitors against Human Peptidyl-Prolyl Isomerase Pin1
Peptidyl-prolyl isomerase Pin1 regulates the function and/or stability of phosphoproteins by altering the conformation of specific pSer/pThr-Pro peptide bonds. In this work, a cyclic peptide library was synthesized and screened against the catalytic domain of human Pin1. The selected inhibitors cont...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841714/ https://ncbi.nlm.nih.gov/pubmed/20180533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901778v |
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