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A kinetic model identifies phosphorylated estrogen receptor-α (ERα) as a critical regulator of ERα dynamics in breast cancer

Receptor levels are a key mechanism by which cells regulate their response to stimuli. The levels of estrogen receptor-α (ERα) impact breast cancer cell proliferation and are used to predict prognosis and sensitivity to endocrine therapy. Despite the clinical application of this information, it rema...

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Bibliografische gegevens
Gepubliceerd in:FASEB J
Hoofdauteurs: Tian, Dan, Solodin, Natalia M., Rajbhandari, Prashant, Bjorklund, Kelsi, Alarid, Elaine T., Kreeger, Pamela K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Federation of American Societies for Experimental Biology 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415015/
https://ncbi.nlm.nih.gov/pubmed/25648997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-265637
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