Direct Evidence for the Formation of Precatenanes during DNA Replication

The dynamics of DNA topology during replication are still poorly understood. Bacterial plasmids are negatively supercoiled. This underwinding facilitates strand separation of the DNA duplex during replication. Leading the replisome, a DNA helicase separates the parental strands that are to be used a...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Cebrián, Jorge, Castán, Alicia, Martínez, Víctor, Kadomatsu-Hermosa, Maridian J., Parra, Cristina, Fernández-Nestosa, María José, Schaerer, Christian, Hernández, Pablo, Krimer, Dora B., Schvartzman, Jorge B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
DNA and Chromosomes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447951/
https://ncbi.nlm.nih.gov/pubmed/25829493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.642272
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