Direct Evidence for the Formation of Precatenanes during DNA Replication

The dynamics of DNA topology during replication are still poorly understood. Bacterial plasmids are negatively supercoiled. This underwinding facilitates strand separation of the DNA duplex during replication. Leading the replisome, a DNA helicase separates the parental strands that are to be used a...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Cebrián, Jorge, Castán, Alicia, Martínez, Víctor, Kadomatsu-Hermosa, Maridian J., Parra, Cristina, Fernández-Nestosa, María José, Schaerer, Christian, Hernández, Pablo, Krimer, Dora B., Schvartzman, Jorge B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
DNA and Chromosomes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447951/
https://ncbi.nlm.nih.gov/pubmed/25829493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.642272
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