Direct Evidence for the Formation of Precatenanes during DNA Replication

The dynamics of DNA topology during replication are still poorly understood. Bacterial plasmids are negatively supercoiled. This underwinding facilitates strand separation of the DNA duplex during replication. Leading the replisome, a DNA helicase separates the parental strands that are to be used a...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Cebrián, Jorge, Castán, Alicia, Martínez, Víctor, Kadomatsu-Hermosa, Maridian J., Parra, Cristina, Fernández-Nestosa, María José, Schaerer, Christian, Hernández, Pablo, Krimer, Dora B., Schvartzman, Jorge B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
DNA and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447951/
https://ncbi.nlm.nih.gov/pubmed/25829493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.642272
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