Direct Evidence for the Formation of Precatenanes during DNA Replication

The dynamics of DNA topology during replication are still poorly understood. Bacterial plasmids are negatively supercoiled. This underwinding facilitates strand separation of the DNA duplex during replication. Leading the replisome, a DNA helicase separates the parental strands that are to be used a...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Cebrián, Jorge, Castán, Alicia, Martínez, Víctor, Kadomatsu-Hermosa, Maridian J., Parra, Cristina, Fernández-Nestosa, María José, Schaerer, Christian, Hernández, Pablo, Krimer, Dora B., Schvartzman, Jorge B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
DNA and Chromosomes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447951/
https://ncbi.nlm.nih.gov/pubmed/25829493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.642272
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