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Adenosine 2A receptor agonism: a single intrathecal administration attenuates motor paralysis in experimental autoimmune encephalopathy in rats

A single intrathecal dose of adenosine 2A receptor (A(2A)R) agonist was previously reported to produce a multi-week reversal of allodynia in two different models of neuropathic pain in addition to downregulating glial activation markers in the spinal cord. We aimed to determine whether a single intr...

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Publicat a:Brain Behav Immun
Autors principals: Loram, Lisa C, Strand, Keith A, Taylor, Frederick R, Sloane, Evan, Van Dam, Anne-Marie, Rieger, Jayson, Maier, Steven F, Watkins, Linda R
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447711/
https://ncbi.nlm.nih.gov/pubmed/25653191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2015.01.014
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