Behavioral assessment of neuropathic pain, fatigue, and anxiety in experimental autoimmune encephalomyelitis (EAE) and attenuation by interleukin-10 gene therapy

Relapsing-remitting multiple sclerosis is commonly associated with motor impairments, neuropathic pain, fatigue, mood disorders, and decreased life expectancy. However, preclinical pharmacological studies predominantly rely on clinical scoring of motor deficit as the sole behavioral endpoint. Thus,...

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Foilsithe in:Brain Behav Immun
Main Authors: Grace, Peter M., Loram, Lisa C., Christianson, John P., Strand, Keith A., Flyer-Adams, Johanna G., Penzkover, Kathryn R., Forsayeth, John R., van Dam, Anne-Marie, Mahoney, Melissa J., Maier, Steven F., Chavez, Raymond A., Watkins, Linda R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108696/
https://ncbi.nlm.nih.gov/pubmed/27189037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2016.05.012
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