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Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
BACKGROUND: The bile acid derivative 6-ethylchenodeoxycholic acid (obeticholic acid) is a potent activator of the farnesoid X nuclear receptor that reduces liver fat and fibrosis in animal models of fatty liver disease. We assessed the efficacy of obeticholic acid in adult patients with non-alcoholi...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Lancet |
|---|---|
| Prif Awduron: | , , , , , , , , , , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2014
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4447192/ https://ncbi.nlm.nih.gov/pubmed/25468160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(14)61933-4 |
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